Endnotes: The Chemical Limitation of the Cortex

Back to TopicsAbstract Feelings and Abstract SensesStart: Relativity & Reaction
– Nerd Cheat Sheet: The Chemical Limitation of the Cortex

These works underpin the discussion of how the cortex and limbic system interact — the chemical and electrical dialogue that shapes emotion, thought, and mood.

They form the factual base for understanding why emotional bias has biological roots and how self-awareness can reframe reaction into reflection.

🧩 Neuroscience and Brain Physiology

Explains the core electrochemical and structural principles of cortical–limbic communication, brain plasticity, and sensory integration.

  • Bear, M. F., Connors, B. W., & Paradiso, M. A. (2020). Neuroscience: Exploring the Brain (5th ed.). Wolters Kluwer.
  • Kandel, E. R., Schwartz, J. H., & Jessell, T. M. (2013). Principles of Neural Science (5th ed.). McGraw-Hill.
  • Logothetis, N. K. (2008). What we can do and what we cannot do with fMRI. Nature, 453, 869–878.
  • Herculano-Houzel, S. (2012). The remarkable, yet not extraordinary, human brain as a scaled-up primate brain. PNAS, 109(Suppl. 1), 10661–10668.
  • Striedter, G. F. (2005). Principles of Brain Evolution. Sinauer Associates.

💭 Emotion, Mood, and Cognitive Regulation

Describes the chemistry of emotion, the limbic system’s role in motivation, and the prefrontal cortex’s capacity for regulation and restraint.

  • Damasio, A. R. (1994). Descartes’ Error: Emotion, Reason, and the Human Brain. Putnam.
  • LeDoux, J. (2012). Rethinking the emotional brain. Neuron, 73(4), 653–676.
  • Fuster, J. M. (2015). The Prefrontal Cortex (5th ed.). Academic Press.
  • Miller, E. K., & Cohen, J. D. (2001). An integrative theory of prefrontal cortex function. Annual Review of Neuroscience, 24, 167–202.
  • 🔄 Learning, Plasticity, and Emotional Conditioning
  • The shaping of emotional bias during development — how early experiences and family modeling influence cortical–limbic patterns.
  • Kolb, B., & Gibb, R. (2011). Brain plasticity and behaviour in the developing brain. Brain Research, 1389, 140–150.
  • Sapolsky, R. M. (2004). Why Zebras Don’t Get Ulcers: The Acclaimed Guide to Stress, Stress-Related Diseases, and Coping. Holt.

⚙️ Applied Perspective

Bridges biology and practice — understanding emotion as a system variable that can be tuned, not suppressed.

  • Kahneman, D. (2011). Thinking, Fast and Slow. Farrar, Straus and Giroux.
  • Thaler & Sunstein (2008). Nudge: Improving Decisions About Health, Wealth, and Happiness.
  • Kahneman, Sibony & Sunstein (2021). Noise: A Flaw in Human Judgment.

🧠 How to Use This Annex

Each of these sources supports the biological logic that underlies human bias and emotion.

They are not required reading but serve as anchors of truth — ensuring that every practical insight about emotion, reaction, and reflection rests on reliable science.


📖 Series Roadmap

  1. Forward: A Little Background
  2. Introduction: Action, Reaction, and the Human Paradox (16.09.2025)
  3. Looking Back in Time: The Development of the Human Brain (23.09.2025)
  4. Abstract Senses: Enhancing the way we see the world outside (30.09.2025)
  5. Bias as a Concept & Climbing the Stairs: Pattern Recognition & Everyday Tasks (07.10.2025)
  6. Abstract Feelings and Abstract Senses (14.10.2025)
  7. Motivation (04.11.2025)
  8. The Social Knowledge Base (11.11.2025)
  9. Potential (18.11.2025)
  10. The Subliminal Way We Go Through Life (26.11.2025)
  11. Taking Responsibility (02.12.2025)
  12. Fishing for Complements (22.12.2025)
  13. Peter and Fermi (22.12.2025)

🔗 R&R Navigation

Back to TopicsAbstract Feelings and Abstract SensesStart: Relativity & Reaction
– Nerd Cheat Sheet: The Chemical Limitation of the Cortex


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